Certificate of Analysis
| Product Name: | IPN60090 |
| Catalog Number: | M10836 |
| CAS Number: | 1853164-83-6 |
Physical and Chemical Properties
| Formula: | C24H27F3N8O3 |
| Molecular Weight: | 532.52 |
| Solubility: | DMSO ≥ 20 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | IPN-60090 (IACS-6274) is an inhibitor of orally active and highly selective glutaminease 1 GLS1 (IC50=31 nM), inactive against GLS-2. IPN-60090 (IACS-6274) exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 can be used in the study of solid tumors such as lung and ovarian cancers. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |