Certificate of Analysis

 

Product Name: HJC0197
Catalog Number: M11263
CAS Number: 1383539-73-8

Physical and Chemical Properties
Formula: C19H21N3OS
Molecular Weight: 339.45
Solubility: DMSO ≥ 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: HJC0197  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: HJC0197 is a potent antagonist of Epac1 (the exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2). HJC0197 selectively blocked camp-induced Epac activation. HJC0197 inhibited epAC1-mediated RAP1-GDP exchange activity in the presence of isoconcentration of cAMP.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.