Certificate of Analysis
| Product Name: | H3B-8800 |
| Catalog Number: | M10693 |
| CAS Number: | 1825302-42-8 |
Physical and Chemical Properties
| Formula: | C31H45N3O6 |
| Molecular Weight: | 555.71 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | H3B-8800 is an orally available small molecule modulator of splicing factor 3B subunit 1 (SF3B1). H3B-8800 binds SF3B1 and exhibits significant antitumor activity by eliminating disruption of mRNA splicing. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |