Certificate of Analysis

 

Product Name: H3B-6527
Catalog Number: M5242
CAS Number: 1702259-66-2

Physical and Chemical Properties
Formula: C29H34Cl2N8O4
Molecular Weight: 629.54
Solubility: ≥ 6.3 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: H3B-6527 Structure
Analytical Data
QC Standard: 99.13%
H-NMR: Consistent with structure
Product Information
Description: H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.