Certificate of Analysis
| Product Name: | GW274150 |
| Catalog Number: | M56380 |
| CAS Number: | 210354-22-6 |
Physical and Chemical Properties
| Formula: | C8H17N3O2S |
| Molecular Weight: | 219.3 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL; Water ≥ 62 mg/mL |
| Storage: | 4°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |