Certificate of Analysis

 

Product Name: GW2580
Catalog Number: M2743
CAS Number: 870483-87-7

Physical and Chemical Properties
Formula: C20H22N4O3
Molecular Weight: 366.41
Solubility: DMSO 28 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GW2580 Structure
Analytical Data
QC Standard: 100.0%
H-NMR: Consistent with structure
Product Information
Description: GW2580 is a selective CSF-1R inhibitor for c-FMS with IC50 of 30 nM, 150- to 500-fold selective compared to b-Raf, CDK4, c-KIT, c-SRC, EGFR, ERBB2/4, ERK2, FLT-3, GSK3, ITK, JAK2 etc.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.