Certificate of Analysis

 

Product Name: GNE-2256 
Catalog Number: M29236
CAS Number: 2102170-43-2

Physical and Chemical Properties
Formula: C24H27FN6O4
Molecular Weight: 482.51
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: GNE-2256  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: GNE-2256 (molecule 19) is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.