Certificate of Analysis

 

Product Name: Gemigliptin
Catalog Number: M20841
CAS Number: 911637-19-9

Physical and Chemical Properties
Formula: C18H19F8N5O2
Molecular Weight: 489.36
Solubility: DMSO 98 mg/mL; Water 12 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Gemigliptin Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Gemigliptin (Zemiglo, LC15-0444) is a potent, selective and long-acting dipeptidyl peptidase 4 (DPP 4) inhibitor with a Ki of 7.25 nM. Gemigliptin shows at least >23,000-fold selectivity for DPP-4 over various proteases and peptidases, including DPP-8, DPP-9, and fibroblast activation protein (FAP)-α.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.