Certificate of Analysis

 

Product Name: RX-3117
Catalog Number: M22390
CAS Number: 865838-26-2

Physical and Chemical Properties
Formula: C10H12FN3O4
Molecular Weight: 257.22
Solubility: DMSO ≥ 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: RX-3117 Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: RX-3117 (TV-1360) is a potent and orally active anticancer and antimetabolite agent. RX-3117 inhibits DNA methyltransferase 1 (DNMT1). RX-3117 shows antiproliferative and anti-tumour activity. RX-3117 induces cell cycle arrest at S phase and apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.