Certificate of Analysis

 

Product Name: Fialuridine
Catalog Number: M8400
CAS Number: 69123-98-4

Physical and Chemical Properties
Formula: C9H10FIN2O5
Molecular Weight: 372.09
Solubility: DMSO 4 mg/mL (warmed)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Fialuridine Structure
Analytical Data
QC Standard: 99.81%
H-NMR: Consistent with structure
Product Information
Description: Fluuridine is a nucleoside antiviral compound. The compound showed significant mitochondrial toxicity. Fialuridine is also a DNA-directed DNA polymerase inhibitor that may be used to treat HBV infection and has potent activity against hepatitis B virus in vivo and in vitro. FIAU blocks DNA synthesis of human cytomegalovirus, hepatitis B and herpes simplex viruses.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.