Certificate of Analysis
| Product Name: | Exarafenib |
| Catalog Number: | M22476 |
| CAS Number: | 2639957-39-2 |
Physical and Chemical Properties
| Formula: | C26H34F3N5O3 |
| Molecular Weight: | 521.58 |
| Solubility: | DMSO 90 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Exarafenib (KIN-2787) is a highly selective, potent, next-generation, pan-RAF inhibitor with activity across BRAF and RAS mutant human tumor cell models. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |