Certificate of Analysis

 

Product Name: Evixapodlin
Catalog Number: M11456
CAS Number: 2374856-75-2

Physical and Chemical Properties
Formula: C34H36Cl2N8O4
Molecular Weight: 691.61
Form: Solid
Solubility: DMSO ≥ 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Evixapodlin Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Evixapodlin (PD-1/ PD-L1-in 7) is an inhibitor of human PD-1/PD-L1 protein/protein interaction with an IC50 of 0.213 nM. Evixapodlin has anti-cancer and anti-virus properties.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.