Product Name: | EG01377 dihydrochloride |
Catalog Number: | M31043 |
Formula: | C26H32Cl2N6O6S2 |
Molecular Weight: | 659.6 |
Form: | Solid |
Solubility: | DMSO 200 mg/mL (ultrasonic) |
Storage: | -20°C, dry, sealed |
QC Standard: | ≥99.0% |
Description: | EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |