Product Name: | Echinomycin |
Catalog Number: | M14448 |
CAS Number: | 512-64-1 |
Molecular Weight: | 1101.26 |
Solubility: | DMSO 5.3 mg/mL |
Storage: | -20°C, sealed |
Chemical Structure: | ![]() |
QC Standard: | >99% |
H-NMR: | Consistent with structure |
Description: | Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |