Certificate of Analysis

 

Product Name: DT2216
Catalog Number: M10423
CAS Number: 2365172-42-3

Physical and Chemical Properties
Formula: C77H96ClF3N10O10S4
Molecular Weight: 1542.36
Solubility: DMSO 20 mg/mL
Storage: -20°C, sealed
Chemical Structure: DT2216 Structure
Analytical Data
QC Standard: 99.11%
H-NMR: Consistent with structure
Product Information
Description: DT2216 is a BCL-XL protein hydrolysis targeting chimera (PROTAC) that ligates and degrades BCL-XL with E3 ubiquitin (E3) ligase. DT2216 is effective against a variety of BCL-XL-dependent leukemias and cancer cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.