Product Name: | Doxorubicin |
Catalog Number: | M29508 |
CAS Number: | 23214-92-8 |
Formula: | C27H29NO11 |
Molecular Weight: | 543.52 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Chemical Structure: | ![]() |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |