Certificate of Analysis

 

Product Name: Doxorubicin
Catalog Number: M29508
CAS Number: 23214-92-8

Physical and Chemical Properties
Formula: C27H29NO11
Molecular Weight: 543.52
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: Doxorubicin Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.