Certificate of Analysis
| Product Name: | Dorsomorphin dihydrochloride |
| Catalog Number: | M2238 |
| CAS Number: | 1219168-18-9 |
Physical and Chemical Properties
| Formula: | C24H25N5O.2HCl |
| Molecular Weight: | 472.41 |
| Solubility: | Water 45 mg/mL; DMSO 5 mg/mL (Need ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.67% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Dorsomorphin (BML-275; Compound C) dihydrochloride is a potent inhibitor of AMP-activated protein kinase (AMPK), with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |