Certificate of Analysis

 

Product Name: Domatinostat tosylate
Catalog Number: M13670
CAS Number: 1186222-89-8

Physical and Chemical Properties
Molecular Weight: 619.71
Solubility: DMSO ≥ 51 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Domatinostat tosylate Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.