Certificate of Analysis
| Product Name: | Recombinant Human DKK-1 (HEK293, N-8His) |
| Catalog Number: | M11533 |
Physical and Chemical Properties
| Form: | Lyophilized powder |
| Solubility: | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage: | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
Analytical Data
| QC Standard: | >95%, Endotoxin＜0.01 EU/ug |
Product Information
| Description: | Dickkopf-related protein 1(DKK-1) secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |