Certificate of Analysis
| Product Name: | CM-579 trihydrochloride |
| Catalog Number: | M21486 |
| CAS Number: | 1846570-40-8 (free base) |
Physical and Chemical Properties
| Formula: | C29H43Cl3N4O3 |
| Molecular Weight: | 602.04 |
| Solubility: | DMSO ≥ 20 mg/mL |
| Storage: | 2-8℃, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | CM-579 trihydrochloride is a dual inhibitor of G9a and DNA methyltransferase (DNMT), with IC50 values of 16 nM and 32 nM, respectively, as first-in-class, reversible. It plays an active role in a variety of cancer cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |