Certificate of Analysis
| Product Name: | CK 666 |
| Catalog Number: | M6611 |
| CAS Number: | 442633-00-3 |
Physical and Chemical Properties
| Formula: | C18H17FN2O |
| Molecular Weight: | 296.34 |
| Solubility: | DMSO 29.63 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.79% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ck-666 is a cell-permeable inhibitor (IC50=12 μM) of the Arp2/3 complex, which binds to the Arp2/3 complex and stabilizes the inactive state of the complex, preventing the movement of Arp2 and Arp3 subunits into the active filamentous conformation. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |