Certificate of Analysis

 

Product Name: C25-140
Catalog Number: M13561
CAS Number: 1358099-18-9

Physical and Chemical Properties
Formula: C26H31N7O
Molecular Weight: 457.57
Solubility: DMSO 62.5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: C25-140 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.