Product Name: | BMS-986122 |
Catalog Number: | M11311 |
CAS Number: | 313669-88-4 |
Formula: | C16H15BrClNO3S2 |
Molecular Weight: | 448.78 |
Solubility: | DMSO ≥ 60 mg/mL |
Storage: | 2-8°C |
Chemical Structure: |
QC Standard: | >98% |
H-NMR: | Consistent with structure |
Description: | Bms-986122 is a selective and effective positive allosteric regulator of μ -opioid receptor (µ-OR). Bms-986122 showed enhancement of β -inhibitory protein recruitment, adenylate cyclase inhibition and G-protein activation mediated by normal agonists. Bms-986122 enhances damGO-mediated [35S]GTPγS binding in mouse meninges. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |