Certificate of Analysis

 

Product Name: BMS-813160
Catalog Number: M6249
CAS Number: 1286279-29-5

Physical and Chemical Properties
Formula: C25H40N8O2
Molecular Weight: 484.64
Solubility: DMSO 20 mg/mL; Ethanol 70 mg/mL
Storage: -20°C, protect from light
Chemical Structure: BMS-813160  Structure
Analytical Data
QC Standard: 99.55%
H-NMR: Consistent with structure
Product Information
Description: BMS-813160 is the first dual CCR2/CCR5 antagonist. BMS-813160 binds with CCR2, CCR5, CCR1, CCR4 and CXCR2 with IC50s of 6.2 nM, 3.6 nM, >25 μM, >40 μM and >40 μM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.