Certificate of Analysis
| Product Name: | (+)-Bicuculline |
| Catalog Number: | M2347 |
| CAS Number: | 485-49-4 |
Physical and Chemical Properties
| Formula: | C20H17NO6 |
| Molecular Weight: | 367.35 |
| Solubility: | DMSO: ≥ 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: | -Bicuculline-chemical-structure.gif) |
Analytical Data
| QC Standard: | 99.74% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |