Certificate of Analysis
| Product Name: | BAY-3827 |
| Catalog Number: | M31105 |
| CAS Number: | 2377576-35-5 |
Physical and Chemical Properties
| Formula: | C27H25FN6O |
| Molecular Weight: | 468.53 |
| Solubility: | DMSO 20 mg/mL (ultrasonic and warming) |
| Storage: | -20°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BAY-3827 is a potent AMPK inhibitor which inhibits AMPK kinase activity with IC50 values of 1.4 nM at low (10 µM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 (ACC1). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |