Certificate of Analysis
| Product Name: | AUNP-12 TFA |
| Catalog Number: | M11421 |
| CAS Number: | 1353563-85-5 (free base) |
Physical and Chemical Properties
| Formula: | C5H17TFIN2O2S2Si |
| Molecular Weight: | 3375.57 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Aunp-12 (NP-12) TFA is a peptide antagonist of the PD-1 signaling pathway, which has an equivalent antagonistic effect on PD-L1 and PD-L2 in terms of inhibiting lymphocyte proliferation and effector function. Aunp-12 TFA has immune-activating effect and good anti-tumor activity, which has the potential to better study immune-related adverse events (irAEs). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |