Certificate of Analysis

 

Product Name: ASK120067
Catalog Number: M13437
CAS Number: 1934259-00-3

Physical and Chemical Properties
Formula: C29H32ClN7O2
Molecular Weight: 546.07
Solubility: DMSO : 41.67 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ASK120067  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: ASK120067 is the third generation EGFR-TKI for non-small cell lung cancer (NSCLC) studies and is an effective oral EGFRT790M inhibitor (IC50 = 0.3 nM) with EGFRWT selectivity (IC50 = 6.0 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.