Certificate of Analysis
| Product Name: | ART812 |
| Catalog Number: | M21558 |
| CAS Number: | 2607138-82-7 |
Physical and Chemical Properties
| Formula: | C19H16ClF4N3O4 |
| Molecular Weight: | 461.79 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ART812 is an orally effective DNA polymerase Polθ inhibitor with an IC50 value of 7.6 nM. ART812 had an IC50 value of 240 nM for cell-based microhomologous mediated end-junction (MMEJ). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |