Certificate of Analysis
| Product Name: | Apilimod mesylate |
| Catalog Number: | M9418 |
| CAS Number: | 870087-36-8 |
Physical and Chemical Properties
| Formula: | C25H34N6O8S2 |
| Molecular Weight: | 610.7 |
| Solubility: | Water 60 mg/mL; DMSO 8 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.52% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Apilimod mesylate is a potent IL-12/IL-23 inhibitor, which inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively Apilimod is also a potent and highly selective PIKfyve inhibitor. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |