Certificate of Analysis

 

Product Name: AMI-1 disodium salt
Catalog Number: M10495
CAS Number: 20324-87-2

Physical and Chemical Properties
Formula: C21H14N2Na2O9S2
Molecular Weight: 548.45
Solubility: DMSO 45 mg/mL; Water 10 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: AMI-1 disodium salt Structure
Analytical Data
QC Standard: 99.60%
H-NMR: Consistent with structure
Product Information
Description: AMI-1 is a potent and selective, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50 values of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 is also a potent scavenger of NADPH-oxidase-derived superoxide.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.