Certificate of Analysis

 

Product Name: α-Hydroxyglutaric acid disodium
Catalog Number: M30059
CAS Number: 40951-21-1

Physical and Chemical Properties
Formula: C5H6Na2O5
Molecular Weight: 192.08
Form: Solid
Solubility: Water 125 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: -20°C, dry, sealed
Chemical Structure: α-Hydroxyglutaric acid disodium Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.