Certificate of Analysis

 

Product Name: Aldumastat
Catalog Number: M10778
CAS Number: 1957278-93-1

Physical and Chemical Properties
Formula: C20H24F2N4O3
Molecular Weight: 406.43
Solubility: DMSO ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Aldumastat  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Aldumastat (GLPG1972; S201086) is a potent, selective, orally active ADAMTS-5 (IC50=19 nM) inhibitor, whose selectivity is ADAMTS-4 (IC50=8 times 156 nM). Aldumastat has antimetabolic activity for osteoarthritis research.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.