Certificate of Analysis
| Product Name: | Afabicin |
| Catalog Number: | M28562 |
| CAS Number: | 1518800-35-5 |
Physical and Chemical Properties
| Formula: | C23H24N3O7P |
| Molecular Weight: | 485.43 |
| Form: | Solid |
| Solubility: | Water 3.85 mg/mL (ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |