Certificate of Analysis
| Product Name: | ABT-384 |
| Catalog Number: | M30757 |
| CAS Number: | 868623-40-9 |
Physical and Chemical Properties
| Formula: | C25H34F3N5O2 |
| Molecular Weight: | 493.56 |
| Form: | Solid |
| Solubility: | DMSO 31.25 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ABT-384 is a potent, selective 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. ABT-384 exhibits high affinity (Ki 0.1-2.7 nM) against rodent, monkey, and human 11β-HSD1. ABT-384 blocks regeneration of active cortisol. ABT-384 can be used for the research of Alzheimer’s disease (AD). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |