Certificate of Analysis

 

Product Name: Y-39983 dihydrochloride
Catalog Number: M5123
CAS Number: 173897-44-4

Physical and Chemical Properties
Formula: C16H18Cl2N4O
Molecular Weight: 353.25
Solubility: DMSO 80 mg/mL; Water 40 mg/mL
Storage: 4°C, dry, sealed
Chemical Structure: Y-39983 dihydrochloride Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Y-39983 (Y-33075) dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM, derived from Y-27632, inhibited ROCK more potently than Y-27632.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.