Certificate of Analysis
| Product Name: | Trimethylamine N-oxide dihydrate |
| Catalog Number: | M54724 |
| CAS Number: | 62637-93-8 |
Physical and Chemical Properties
| Formula: | C3H13NO3 |
| Molecular Weight: | 111.14 |
| Form: | Solid |
| Solubility: | Water 100 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients.Trimethylamine N-oxide dihydrate induces inflammation by activating ROS/NLRP3 inflammasome, and also accelerates fibroblast differentiation and induces cardiac fibrosis by activating TGF-β/smad2 signaling pathway. In addition, Trimethylamine N-oxide dihydrate induces tumor cell pyroptosis and enhances CD8+ T cell-mediated antitumor responses in triple-negative breast cancer. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |