Certificate of Analysis
| Product Name: | Takinib |
| Catalog Number: | M6310 |
| CAS Number: | 1111556-37-6 |
Physical and Chemical Properties
| Formula: | C18H18N4O2 |
| Molecular Weight: | 322.36 |
| Solubility: | DMSO 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.69% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |