Certificate of Analysis


Catalog Number: M2572
Product Name: SMI-4a
CAS Number: 438190-29-5

Physical and Chemical Properties
Formula: C11H6F3NO2S
Molecular Weight: 273.23
Solubility: DMSO 50 mg/mL
Long-term Storage: at -20°C
Chemical Structure: SMI-4a Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM, modest potent to Pim-2, does not significantly inhibit other serine/threonine- or tyrosine-kinases.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.