Certificate of Analysis

 
Product Name: Samuraciclib hydrochloride
Catalog Number: M10886
CAS Number: 1805789-54-1
Physical and Chemical Properties
Formula: C22H31ClN6O
Molecular Weight: 430.98
Solubility: DMSO ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Samuraciclib hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Samuraciclib (ICEC0942, CT7001) is a novel oral CDK7 inhibitor with an IC50 of 40 nM. It has IC50 values for other CDK proteins such as CDK1, CDK2, CDK5 and CDK9 as 45, 15, 230 and 30 times higher than that of CDK7 IC50, respectively. ICEC0942 (CT7001) promotes cell cycle blocking and apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.