Certificate of Analysis

 

Catalog Number: M5944
Product Name: Ruxolitinib phosphate
CAS Number: 1092939-17-7

Physical and Chemical Properties
Formula: C17H21N6O4P
Molecular Weight: 404.36
Solubility: 31 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Ruxolitinib phosphate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.