Certificate of Analysis

 

Catalog Number: M11017
Product Name: RP-3500
CAS Number: 2417489-10-0

Physical and Chemical Properties
Formula: C₂₁H₂₆N₆O₃
Molecular Weight: 410.47
Solubility:
Storage: at -20°C
Chemical Structure: RP-3500 Structure
Analytical Data
HPLC: Shows Min purity
H-NMR: Consistent with structure
Product Information
Description: RP-3500 (ATR inhibitor 4) is an orally potent, selective ATR kinase inhibitor (ATRi) in biochemical assays IC50 1.00 nM. The RP-3500 is 30 times more selective to ATR (IC).50=120 nM), which is 2,000 times > ATM, DNA-PK, and PI3Kα kinase.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.