Certificate of Analysis


Catalog Number: M2590
Product Name: Purvalanol B
CAS Number: 212844-54-7

Physical and Chemical Properties
Formula: C20H25ClN6O3
Molecular Weight: 432.91
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: Purvalanol B Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.