|Product Name:||PD 0332991 HCL|
|Solubility:||30 mg/mL in water|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min 99.90% purity|
|H-NMR:||Consistent with structure|
|Description:||PD-0332991 HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.