Certificate of Analysis

 

Catalog Number: M8926
Product Name: Niraparib (MK-4827) tosylate
CAS Number: 1038915-73-9

Physical and Chemical Properties
Formula: C19H20N4O.C7H8O3S
Molecular Weight: 492.59
Solubility: DMSO: ≥ 60 mg/mL
Long-term Storage: at -20°C
Chemical Structure: Niraparib (MK-4827) tosylate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Niraparib (MK-4827) tosylate is an excellent PARP1 and PARP2 inhibitor with IC50 of 3.8 and 2.1 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.