Certificate of Analysis


Catalog Number: M5279
Product Name: NCB-0846
CAS Number: 1792999-26-8

Physical and Chemical Properties
Formula: C21H21N5O2
Molecular Weight: 375.42
Solubility: 75 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: NCB-0846 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.