Certificate of Analysis
| Product Name: | Mavacamten (MYK-461) |
| Catalog Number: | M10262 |
| CAS Number: | 1642288-47-8 |
Physical and Chemical Properties
| Formula: | C15H19N3O2 |
| Molecular Weight: | 273.33 |
| Solubility: | DMSO 65 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.80% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Mavacamten, also known as SAR-439152 and MYK-461, is the first (first-class) orally bioavailable allosteric and reversible selective inhibitor of Cardiac Myosin. The IC50 of bovine heart and human heart was 490 nM and 711 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |