Certificate of Analysis

 

Catalog Number: M1801
Product Name: KU-55933
CAS Number: 587871-26-9

Physical and Chemical Properties
Formula: C21H17NO3S2
Molecular Weight: 395.49
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: KU-55933 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.