Certificate of Analysis


Catalog Number: M1730
Product Name: ITF2357
CAS Number: 732302-99-7

Physical and Chemical Properties
Formula: C24H27N3O4.HCl.H2O
Molecular Weight: 475.97
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: ITF2357 Structure
Analytical Data
HPLC: Shows Min 98.20% purity
H-NMR: Consistent with structure
Product Information
Description: ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.