Certificate of Analysis

 

Product Name: GCN2iB
Catalog Number: M13661
CAS Number: 2183470-12-2

Physical and Chemical Properties
Formula: C18H12ClF2N5O3S
Molecular Weight: 451.83
Form: Solid
Solubility: DMSO 45 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GCN2iB Structure
Analytical Data
QC Standard: 98.86%
H-NMR: Consistent with structure
Product Information
Description: GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.